LC/MS Sample Prep Scientist

Talentmark are recruiting for a LC-MS Sample Prep Scientist to join a precision medicine company based near Manchester on a permanent basis.

Company: Our client is developing next-generation diagnostic tests to help clinicians prescribe the right drug, for the right patient, at the right time. They are developing LC-MS proteomic biomarker discovery platforms and clinical assays to predict drug response in a clinical setting.

The Role:

You will support the development of clinical assays for biomarkers by preparing samples for LC-MS analysis

Responsibilities:

• Perform analysis of clinical samples to identify new biomarkers for emerging drugs of interest.
• Coordinate with management and other members of the technical team so that sample analyses are scheduled and performed in a timely manner.
• Assist with the experimental component of projects, including experimental design, sample preparation optimisation and automation, and data interpretation.
• Assist with the maintenance of cell line stocks and generation of samples for method development and QC.
• Make process improvements and project efficiencies wherever possible and contribute freely to the team environment in a manner conducive to the success of company goals.
• Work with the product development team and quality manager to ensure appropriate systems, monitoring and documentation are in place during development of a test.
• Handling and management of samples, including organising storage, database logging and safe disposal.

• Educated to PhD level in a relevant field such as proteomics or protein biochemistry applied to the investigation of mammalian cell biology.
• Hands-on experience in sample preparation using proteomic workflows for LC-MS/MS analysis.
• Experience working with multiple sample types (e.g. cell lines, blood, fresh-frozen and/or FFPE tissue).
• Experience working to GLP standards and/or in an HTA-qualified environment.
• Knowledge and understanding of fundamental principles of biochemical and molecular biological systems.
• Ability to plan and execute experiments and analyses: possesses strong problem-solving abilities with an analytical mindset, and a logical approach to troubleshooting technical challenges.

For more information, or to apply for this position please contact Mary Bolt on 01246 457729 or email mbolt@talentmark.co.uk. Please quote job reference 199158 in all correspondence.

It is essential that applicants hold entitlement to work in the UK